Making decisions at times of uncertainty, by Nils-Eric Sahlin MAE

Making decisions at times of uncertainty, by Nils-Eric Sahlin MAE



Nils-Eric Sahlin MAE tells us about his research on decision-making under conditions of uncertainty, and his contribution to the recent evidence review on ‘Making Sense of Science for Policy’, coordinated by Academia Europaea.

About Nils-Eric Sahlin MAE

Professor Nils-Eric Sahlin MAE is the former Chair of the Swedish Research Council’s Expert Group on Ethics and a current member of the European Group on Ethics in Science and New Technologies (EGE).  He was a member of the SAPEA international working group that produced the Evidence Review Report, Making Sense of Science for Policy under Conditions of Complexity and Uncertainty (SAPEA, 2019), which was coordinated by Academia Europaea.


The interview

You are Professor of Medical Ethics at Lund University (Sweden). Could you tell us more about the work of your department?

“I’m basically a philosopher by training. In the course of my research I’ve studied decision theory, looking especially at the question of how sound decisions are made. I developed quasi-mathematical theories which I hope can be used to guide decision-making, particularly under conditions of great uncertainty. Uncertainty is unavoidable in healthcare, where tough decisions sometimes have to be taken in situations where the underlying information and knowledge is not robust. The Covid-19 pandemic is an example of that.

In my department at Lund, we conduct research in medical ethics. The topics include stem cell use, prioritisation in healthcare, research ethics and informed consent. It’s a fairly small department, but we collaborate with other researchers across the University, and with government agencies, as well as undertaking work at a European level. Until 2019 I was Chair of the Swedish Research Council’s Expert Group on Ethics, and I am presently a member of the Swedish National Council on Medical Ethics. I also serve on the European Group on Ethics.”

Your research portal shows that you have published on a range of interconnected topics over the course of your career. Could you give us an overview of your evolving research interests?

“I’m a curious and restless person, and many things have caught my attention. I’ve been very privileged in my career in having the opportunity to conduct research on topics and themes I believe to be important. I’ve worked on decision-making in its various forms on and off since the late 1970s. A colleague and I developed a theory showing how we should take decisions under conditions of imperfect knowledge. After that we became interested in risk analysis, and specifically epistemic risk, which focuses on certainty – how much do we know, what don’t we know, and how stable is our knowledge? These themes are explored in some of the chapters of the Making Sense of Science for Policy report.

New areas like nanotechnology and gene editing are fascinating. They have huge potential, but the potential is permeated by risk, because our knowledge is limited and attended by uncertainties. This is challenging, because we need to make stable, robust and sound decisions. I’ve been interested in this kind of problem since I started in academia, partly as a result of my background in epistemology, metaphysics and the philosophy of science. There is also a connection here with the work I did on the philosophy of Frank Ramsey, a British philosopher, who died in 1930 aged only 26. Ramsey is a philosopher’s philosopher, and one of the greats of the 20th century. ln my work, I proposed that he developed a peculiarly British form of pragmatism, differing in important ways from the American pragmatism associated with Charles Peirce and William James.”

What are you working on at the moment?

“Recently, two colleagues and I wrote a paper on objective probabilities. We’d been thinking about a world with objective uncertainties and wondering what that would look like. I began to think about this problem in the late 1970s, and thanks to the help of my two colleagues I finally arrived at a solution I was satisfied with.

Right now, we are running an international research programme on ‘science and proven experience’. In Sweden, this is a legal concept. It can be seen in healthcare legislation, which requires doctors to base their decisions on science and proven experience. New methods, techniques and interventions in healthcare should only be implemented when they have been tested and found to accord with science and proven experience. That makes several questions pressing. What do we mean by science and proven experience? What is science? What is proven experience? And how do we understand the connection between them?  Are both needed? It isn’t hard to find examples in healthcare where proven experience appears to be applied in the absence of science, at least if we take randomized controlled trials to be the hallmark of science. Digitalis from the foxglove plant was used for many years to treat heart problems, long before there was scientific evidence for its efficacy.

We have just completed an empirical study involving two large surveys of healthcare professionals. The aim was to understand how the professionals view science and proven experience, and to gauge the importance of proven experience in their daily working lives.”

You were a member of the SAPEA working group that produced the report Making Sense of Science for Policy. What was your focus in the report?

“My main role was to review and comment on various drafts of the report. The Chair Ortwin Renn and others worked very hard on it. I contributed to the sections on risk and decision-making, and I wrote parts dealing with the communication of science.”

You are a member of the European Group on Ethics. What does that involve?

“The Group is an independent advisory body that gives advice to the President of the European Commission. We do so on questions arising from new technologies and scientific endeavours. We recently wrote a statement on Covid-19 in which we tried to clarify the distinctive ethical issues the pandemic has raised. We’ve also published a statement on AI, and a report on the future of work, and we are currently working on gene editing.  The goal here is to look at a wide spectrum of editing types. We will focus specifically on value questions. Our aim is to address the fundamental ethical questions that become unavoidable where values conflict, and specifically questions about the impact of value conflict on decision-making, risk management and governance. You can’t make sense of science without making sense of the underlying ethical questions.”


More information

You can find the the Making Sense of Science for Policy reports on the SAPEA website.



20th April 2020. For further information please contact AECardiffHub@cardiff.ac.uk
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